Free ACLS sample questions

Real questions from the Advanced Cardiac Life Support practice bank, with the correct answer and an explanation for each one. No junk, no filler.

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Showing 9 of 18 free sample questions.

Question 1Choose one

A patient with a regular, wide-complex tachycardia at a rate of 180/min becomes acutely hypotensive with a BP of 70/40 mmHg and shows signs of poor perfusion. The team prepares for synchronized cardioversion, and more than one shock may be needed. Which error is the most dangerous when delivering a repeat synchronized shock?

Question 2Choose one

True or False: According to current AHA ACLS guidelines, routine administration of sodium bicarbonate to counteract acidosis during a typical cardiac arrest is strongly recommended.

Question 3Choose one

A 55-year-old female presents with symptomatic bradycardia at a rate of 40/min. She is diaphoretic and has a BP of 88/50 mmHg. The monitor shows a third-degree AV block. Two doses of atropine 1 mg IV have been administered with no improvement. What is the next most appropriate intervention?

Question 4Choose one

A hospital's resuscitation quality improvement committee is reviewing data from recent cardiac arrest events. They want to assess the effectiveness of chest compressions using quantitative waveform capnography. Which ETCO2 value is the minimum threshold that indicates high-quality CPR?

Question 5Choose one

A patient arrives at the emergency department with symptoms suggestive of an acute stroke. The initial non-contrast CT scan of the head is negative for hemorrhage. The patient meets all other criteria for fibrinolytic therapy. According to the ACLS Suspected Stroke Algorithm, IV fibrinolytic therapy (alteplase or tenecteplase) should be started within what timeframe from the onset of symptoms?

Question 6Choose one

**Case Study** A 72-year-old male is brought to the ED with a chief complaint of severe, crushing substernal chest pain that began 45 minutes ago. He has a history of hypertension and type 2 diabetes. His initial vital signs are BP 160/95 mmHg, HR 95 bpm, RR 22/min, and SpO2 96% on room air. He is given 324 mg of aspirin to chew. A 12-lead ECG is immediately obtained and shows 4 mm ST-segment elevation in leads V2, V3, and V4. The facility has a cardiac catheterization lab that is currently available and staffed. The estimated door-to-balloon time is 60 minutes. Which of the following is the most appropriate next step in the management of this patient?

Question 7Choose one

A patient in cardiac arrest has been intubated with an endotracheal tube. The ventilator is set to deliver 10 breaths per minute. During CPR, chest compressions should be performed at a rate of 100-120 per minute and be ______ with ventilations.

Question 8Choose 3

In the 2025 AHA Chain of Survival, the last link is 'Recovery and Survivorship'. Which of the following are essential components of this link? (Select ALL that apply)

Question 9Choose one

A 40-year-old patient is in refractory ventricular fibrillation despite multiple shocks and 300 mg of amiodarone. The team is considering an alternative antiarrhythmic. What is the correct initial dose of lidocaine for this situation?

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